Which of the following symptoms has been associated with high-intensity exercise in individuals taking prescription statin drugs for dyslipidemia?

Myalgia, or muscle pain, has been widely documented as a symptom associated with statin use, particularly at high-intensity exercise levels. Statins, prescribed to lower cholesterol levels and manage dyslipidemia, can lead to muscle-related side effects in some individuals. During high-intensity exercise, the strain and stress placed on muscles can exacerbate these issues, leading to discomfort or pain.

Research indicates that individuals on statin therapy may have an increased risk of developing muscle-related symptoms, including myalgia, especially when engaging in vigorous activities. Muscle pain can stem from various factors, such as mitochondrial dysfunction or altered muscle metabolism caused by statins, which can contribute to soreness or fatigue after rigorous physical activity.

While fatigue, dizziness, and muscle cramping are noteworthy symptoms that may occur during or after exercise, they are not as specifically linked to statin use as myalgia is. For individuals taking statins, myalgia remains a primary concern, particularly in the context of high-intensity physical activity where muscle demand is significantly increased.